(capsaicin cream 0.025%)
Zacin® (capsaicin cream 0.025%) is for the symptomatic relief of pain associated with osteoarthritis.1
Zacin® (capsaicin cream 0.025%) is for topical application.1
Capsaicin renders skin insensitive to pain by depleting and preventing re-accumulation of Substance P in peripheral sensory neurons.1
For the full list of excipients, see Section 6.1 of the Summary of Product Characteristics.
Significant reduction in pain at two weeks vs placebo2
No interaction studies have been performed, see Section 4.5 of the Summary of Product Characteristics.1
Clinical studies have shown no drug interactions3 with Zacin® (particularly beneficial in patients on multiple drug regimens e.g. the elderly).2
Cephalon UK Limited
Ridings Point, Whistler Drive
Castleford, West Yorkshire
Marketing Authorisation Number(s)
1 Zacin® (capsaicin cream 0.025%) Summary of Product Characteristics.
2 Deal CL, Schnitzer TJ, Lipstein E, et al. Treatment of arthritis with topical capsaicin: a double-blind trial. Clin Ther 1991; 13: 383-393.
3 Schnitzer TJ, Morton C, Coker S, et al. Topical capsaicin for osteoarthritis pain: achieving a maintenance regimen. Semin Arthiritis Rheu 1994; 23 (Suppl. 3): 34-40.
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