Each pre-filled syringe contains 6mg of lipegfilgrastim* in 0.6mL solution. Each ml of solution for injection contains 10mg of lipegfilgrastim.1
*This is based on protein content only. The concentration is 20.9mg/mL (i.e. 12.6mg per pre-filled syringe) if the PEG moiety and the carbohydrate linker are included.1Therapeutic indications
Lonquex® is indicated for the reduction in the duration of neutropenia and the incidence of febrile neutropenia in adult patients treated with cytotoxic chemotherapy for malignancy (with the exception of chronic myeloid leukaemia and myelodysplastic syndromes).1
Lonquex® is approved for restricted use by the Scottish Medicines Consortium and the All Wales Medicines Strategy Group where a long-acting G-CSF is appropriate2,3
Lipefilgrastim is a covalent conjugate of filgrastim** with methoxy polyethylene glycol (PEG) via a carbohydrate linker.1
**Filgrastim (recombinant methionyl human granulocyte-colony stimulating factor [G-CSF]) is produced in Escherichia coli cells by recombinant DNA technology.1
The potency of this medicinal product should not be compared with the potency of another pegylated or non-pegylated protein of the same therapeutic class.1
For more information, see Section 5.1. of the Summary of Product Characteristics.
UAB "Sicor Biotech"
Molėtų pl. 5
Marketing Authorisation Number(s)
1 Lonquex®▼ (lipegfilgrastim) Summary of Product Characteristics.
2 https://www.scottishmedicines.org.uk/SMC_Advice/Advice/908_13_lipegfilgrastim_Lonquex/lipegfilgrastim_Lonquex [accessed 08.04.18].
3 http://www.awmsg.org/awmsgonline/app/appraisalinfo/1297 accessed [08.04.18].
To access this section of the Teva UK Limited website you need to be a member of the healthcare profession
because the materials included in this area of our website are specifically prepared for that audience
To understand why that is - please visit: Working in a regulated environment
Please click on the appropriate button below to confirm that you are healthcare professional.
If you are not a healthcare professional, you will be taken to an area of the website that is appropriate for you.