Ajovy®&#9660 (fremanezumab)

This information is only for patients who have been prescribed AJOVY®

AJOVY® is a prescription medicine containing the active substance fremanezumab, and is used to prevent migraine in adults who have at least four migraine days per month. It is a type of treatment called a monoclonal antibody (mAb) and has been developed in response to the latest understanding of the underlying causes of migraine.

AJOVY® reduces the frequency of migraine attacks and days with headache. This medicine also decreases the disability associated with migraine and it reduces the need for medicines used to treat migraine attacks.

AJOVY® can be taken by injection either monthly or quarterly, as instructed by your doctor. Do not take AJOVY® until you have been shown how to inject by a medical professional.

How does AJOVY® work?

When starting a new treatment for migraine, it can be helpful to know a little about how migraines occur and how your medicine works.

For migraine sufferers, a substance in the body called calcitonin gene-related peptide (CGRP) plays a key role. It is a molecule found in the brain and nervous system and its release is involved in transmitting pain. When CGRP binds to its receptors in the brain, it sets off a chain of events that play an important role in causing migraines. People who have migraines have high levels of CGRP during a migraine attack.

AJOVY® is a CGRP-inhibitor. It works by attaching to CGRP, to stop it from binding to its receptor. This prevents the chain of events that contribute to migraines, which can result in fewer or less severe migraines. Learn more in this video animation.

How to inject AJOVY® pre-filled syringe

AJOVY® is given by injection under your skin (subcutaneous injection). To help you get started, your doctor or nurse will explain to you or your caregiver how to give the injection safely and comfortably. Please do not try to inject AJOVY® until you or your caregiver have been trained.

How to inject AJOVY® pre-filled pen

Please read the AJOVY® Pre-filled Pen Quick Tips Guide in conjunction with viewing the AJOVY® Pre-filled Pen training video.

Further information and support

Patient Information Leaflet

Download from product list

To contact Teva's Medical Information Service:

Contact us

Rain Free Days® - Patient Support Programme app

Download from Apple Store

Rain Free Days® - Patient Support Programme app

Download from Google Play

 Medicines showing this symbol are subject to additional monitoring. This will allow quick identification of new safety information. You can help by reporting any side effects experienced. If you experience any side effects (adverse events), talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in the package leaflet.

See Yellow Card Scheme for how to report side effects, side effects may also be reported directly to Teva using the Reporting Side Effects Form or e-mail uk.safety@tevauk.com

Life Effects™ - By patients, for patients

The only people who really know what you’re going through are other patients like you. Through Teva’s Life Effects™ website you can read stories, tips and real life experiences from other patients living with migraine.

Discover more Life Effects™ - By patients, for patients
Date of preparation February 2022
Reference: AJO-GB-NP-00117